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UC Irvine School of Medicine is implementing the OnCore Clinical Trials Management System (CTMS), a software system designed to help researchers track financial, subject and regulatory information.

Many major academic centers, including other University of California medical centers, have benefited from OnCore's sophisticated analytics tools. The system's implementation at UC Irvine is being led by the School of Medicine OnCore Support Team, in partnership with Enterprise Data & Analytics, Research Revenue Integrity, and pilot departments/centers that conduct clinical research across UC Irvine.

We encourage you to bookmark this page to view regular updates and find resources related to full implementation of our OnCore system.

What is OnCore?

OnCore is a web-based data system to support efficient and accurate research performance at academic medical centers, cancer centers and other health systems. It enables research teams and departments to aggregate, filter, review and manage data by protocol, subject, contract and organizational unit.

With OnCore, study teams and research administrators can streamline workflows and subject data, as well as gain immediate insight into activities across all protocols.

Standardized information tracking assures research sponsors that investigators and study teams are proactively managing research quality assurance. Accrual status, approval time and staff workload questions become easier to answer and efficiencies become easier to identify. 

Benefits of OnCore

Lead researchers, study teams, managers and administrators encounter many administrative complexities in managing growing clinical trial portfolios. OnCore can help to reduce or even eliminate such challenges in the following ways:

  • Enterprise-level reporting allows institutional leaders to easily gather research metrics to help drive business-level decision-making.
  • Subject management and visit tracking functions allow research teams to track enrollment, schedule subjects within allowable protocol parameters, and monitor study payment milestones.
  • The easy-to-use web-based system facilitates investigator management of multi-center trials.

Key Features

OnCore incorporates a variety of functions that support our researchers and enhance their effectiveness. These include:

  • Shared-records access that minimizes administrative burdens by giving team members access to the same study records, all of which are electronically secured and have access levels managed by system security
  • An interface with the research subject's electronic medical record, which facilitates enrollment tracking and billing compliance
  • Study performance reporting, which gives lead researchers and study coordinators insight into recruitment and accrual information
  • Subject and protocol reports, which facilitate annual and ad hoc IRB safety reports, accrual reporting and sponsor reporting
  • Financial management tools, including integrated budgeting and invoicing, that improve financial performance and billing compliance
  • Tracking of registries and biospecimens that enables data capture and de-identification for sharing and analysis
  • The ability to export of protocol information to the UC Irvine clinical trials website, which can increase awareness and improve recruitment

Transition to OnCore

Subject management

The School of Medicine OnCore Support Team is available to train all study teams on subject management in OnCore, as well as related research functions in EPIC.

Protocol and subject-management training

School of Medicine trainers are available on Wednesdays from 2pm-4pm in the Grunigen Medical Library Instructional Technology Classroom (Orange) to:

  • Answer your questions
  • Provide hands-on, one-on-one problem-solving assistance
  • Integrate your feedback into the system rollout

To RSVP for this training, please complete the OnCore Training Request Form, or email us at to schedule another time and/or location that works for your group.